Who is a pathologist?--- In routine practice, they are Doctors to Doctors and Physician's Physician.- involved in diagnosis and assisting in the management of patients. The scenario has changed dramatically over the years with emergence of newer techniques and ancillary studies like molecular pathology, especially in oncology where targeted therapy is the most sought after tool. Pathologists are now multifaceted with added responsibilities of lab management, financial planning, technology development, and sometimes need to counsel the patients and Doctors as well. The challenges faced mostly relate to inter lab variations in reports.- the reasons are very many.-sampling technique, methodology adopted,the type of instrument used etc.. There has been a number of studies regarding inter lab comparison and quality management. The biological reference interval and the method adopted are important to assess the validity and authenticity of the report. For certain investigations
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